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Bio-restorative Skin Cream

Development stage
Unknown
Lead developer
Merz Aesthetics
Modality
Cytokines & Interferons → Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

Bio-restorative Skin Cream (marketed as Bio•Cream) is a topical biologic skincare product developed by Neocutis (a Merz Aesthetics brand). Its primary active component is Processed Skin Proteins (PSP), a proprietary blend of human growth factors, cytokines, and interleukins derived from cultured skin cells. The cream is designed to promote skin rejuvenation, tissue repair, and inflammatory modulation by stimulating collagen and elastin production. Beyond its widespread use as an anti-aging and post-procedure restorative treatment, it has been evaluated in a Phase 4 clinical trial for the treatment of vulvar vestibulitis syndrome (VVS) and is used to alleviate symptoms of atopic and irritative eczema, such as pruritus, erythema, and edema.

Brand names
Bio•CreamNeocutis Bio-restorative Skin Cream
Other names
PSPProcessed Skin Proteins
02

Targets

Cr (Chromium)AXL (AXL receptor tyrosine kinase)IL (Interleukins)

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