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Drug intelligence / Profile preview
Biocurcumax
- Development stage
- Phase 2
- Lead developer
- Arjuna Natural
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Biocurcumax (also known as BCM-95 or Curcugreen) is a proprietary, high-bioavailability turmeric extract developed by Arjuna Natural Extracts Ltd. It is composed of 95% curcuminoids complexed with turmeric essential oils, specifically standardized to 45% ar-turmerone, which enhances the absorption of curcumin by approximately seven-fold compared to standard extracts. Curcumin, the primary bioactive component, exerts therapeutic effects by modulating multiple signaling pathways, including the inhibition of nuclear factor-kappa B (NF-kB), cyclooxygenase-2 (COX-2), and 5-lipoxygenase (5-LOX), as well as reducing levels of pro-inflammatory cytokines like TNF-alpha and IL-6. Biocurcumax has been clinically evaluated for a variety of conditions, including rheumatoid arthritis, osteoarthritis, major depressive disorder, and as an adjunct treatment for malaria.
- Brand names
- BiocurcumaxCurcugreenBCM-95BCM95BCM 95
- Other names
- curcuminoids with turmeric essential oilcurcumin with ar-turmerone
02
Targets
PTGS2 (Prostaglandin-Endoperoxide Synthase 2)NF-κBALOX5 (Arachidonate 5-lipoxygenase)IL-6 (Interleukin 6)TNFA (Tumor necrosis factor alpha (soluble))
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