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BioCyst
- Development stage
- Unknown
- Lead developer
- CytoChemia
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
BioCyst is an oral phytotherapeutic combination developed by CytoChemia for the prevention and supportive treatment of urinary tract infections (UTIs). The formulation primarily consists of cranberry extract and D-mannose, which work synergistically to maintain bladder health. Cranberry extract contains proanthocyanidins (PACs) that interfere with the P-fimbriae of uropathogenic *Escherichia coli* (UPEC), while D-mannose acts as a competitive inhibitor of Type 1 fimbriae. Together, these components prevent bacteria from adhering to the urothelial cells of the bladder wall, facilitating their clearance through urine. This non-antibiotic approach is particularly utilized for UTI prophylaxis in patients with recurrent infections to reduce reliance on antimicrobial agents. It is marketed in Germany as a dietary supplement intended for long-term urinary tract support.
- Brand names
- BioCyst
02
Targets
P fimbriaeFimH (Type 1 fimbrial adhesin)
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