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Biodase-SP is an oral combination medication developed by PRG Pharma for the management of pain and inflammation. It contains two primary active ingredients: diclofenac potassium and serratiopeptidase. Diclofenac potassium is a nonsteroidal anti-inflammatory drug (NSAID) that acts as a non-selective inhibitor of cyclooxygenase enzymes (COX-1 and COX-2), thereby reducing the synthesis of prostaglandins that mediate pain, fever, and inflammatory responses. Serratiopeptidase is a proteolytic enzyme derived from the bacterium *Serratia marcescens* that exhibits anti-inflammatory, anti-edemic, and fibrinolytic properties. It works by breaking down abnormal proteins and inflammatory mediators at the site of injury, which helps reduce swelling and promotes tissue repair. Biodase-SP is indicated for various painful conditions, including muscle aches, joint pain, dental pain, and post-operative inflammation.
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