Drug intelligence / Profile preview

BioFe

Development stage
Preclinical
Lead developer
Sidero Bioscience
Modality
Recombinant Proteins and Enzymes
Administration
Oral
01

Overview

BioFe is a medical food and nutritional supplement developed by Sidero Bioscience for the management of iron deficiency and iron deficiency anemia (IDA). It consists of a ferritin-based iron complex produced using nutritional yeast (*Saccharomyces cerevisiae*) that expresses high levels of H-Ferritin (FTH1), a natural iron transport and storage protein. This complex mimics the natural ferritin:iron structure found in human breast milk. BioFe utilizes the proprietary Siderosorb platform technology to provide bioavailable iron through an alternate absorption pathway that is not inhibited by inflammation (hepcidin-independent), potentially reducing the gastrointestinal side effects associated with traditional oral iron salts. It is specifically designed for patients who may not tolerate or respond to standard iron supplements, including those with chronic inflammatory conditions.

Brand names
BioFe
Other names
Ferritin:Iron complexH-ferritin derived iron complexferritin-based iron complex
02

Targets

FTH1 (Ferritin heavy chain 1)

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