Drug intelligence / Profile preview

bioidentical hormone pellet implants

Development stage
Unknown
Lead developer
Biote
Modality
Small Molecules
Administration
Implant, Subcutaneous
01

Overview

Bioidentical hormone pellet implants, developed by Segal Pharma Group and its subsidiary Luminera Pharm, are a form of hormone replacement therapy (HRT) used to address symptoms of menopause and general hormonal decline. These compounded drugs consist of hormones such as estradiol or testosterone that are chemically identical to those naturally produced by the human body. The therapy involves the subcutaneous implantation of small pellets, typically in the hip or abdominal area, which provide a sustained, long-term release of hormones into the bloodstream over several months. This delivery method is designed to maintain stable physiological hormone levels, avoiding the fluctuations often associated with oral or topical administrations, and bypassing first-pass hepatic metabolism.

Brand names
Luminera PharmEpidaris
Other names
BHRT pelletssubcutaneous hormone pelletsbioidentical hormone replacement therapy pellets
02

Targets

ESR1 (ERα)ESR2 (ERβ)AR (Adrenergic receptors)

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