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BioLink018
- Development stage
- Unknown
- Lead developer
- Protheragen
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
BioLink018 is a monoclonal antibody directed against CD79B (B-cell antigen receptor complex-associated protein beta chain), a surface protein exclusively expressed on B cells and their malignant counterparts. Developed by Protheragen, the agent is currently in Phase I clinical trials for the treatment of Non-Hodgkin lymphoma (NHL). By targeting CD79B, BioLink018 aims to provide a highly specific therapeutic approach for B-cell malignancies, potentially through mechanisms such as antibody-dependent cellular cytotoxicity (ADCC) or direct signaling inhibition. CD79B is a validated target in hematologic oncology, notably as the target of the antibody-drug conjugate polatuzumab vedotin.
- Other names
- BioLink018BioLink-018BioLink 018
02
Targets
B-cell antigen receptor complex-associated protein beta chain
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