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BioLink1052

Development stage: Unknown
Lead developer: Protheragen
Modality: Fc-Fusion Proteins → Carrier/Scaffold Proteins → Recombinant Proteins and Enzymes
Administration: Subcutaneous

Overview

BioLink1052 is a recombinant fusion protein designed as a dual agonist of the glucagon-like peptide-1 receptor (GLP-1R) and the fibroblast growth factor 21 (FGF21) pathway. Developed by Protheragen, this therapeutic candidate aims to leverage the synergistic effects of GLP-1 and FGF21 to improve glycemic control, promote weight loss, and enhance lipid metabolism in patients with metabolic diseases. GLP-1 receptor activation stimulates insulin secretion and suppresses appetite, while FGF21 signaling improves insulin sensitivity and energy expenditure. BioLink1052 is currently in Phase I clinical development for the treatment of type 2 diabetes and obesity.

Other names: BioLink1052 Fusion ProteinBioLink-1052 Fusion ProteinBioLink 1052 Fusion Protein

Targets

FGFR1 (Fibroblast growth factor receptor 1)GLP1R (GLP-1R)

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