Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Bionanomatrix-CS
- Development stage
- Preclinical
- Lead developer
- Endomimetics
- Modality
- Nanoparticles → Drug Delivery Systems, Peptides
- Administration
- Implantable Device Coating
01
Overview
Bionanomatrix-CS is a peptide-based nanomatrix coating developed by Endomimetics for coronary stents to treat coronary artery disease. The coating is composed of self-assembling peptide amphiphiles that form a structure mimicking the natural endothelium. It is designed to provide sustained, local delivery of nitric oxide (NO) over a period of approximately two months. The mechanism of action involves NO-mediated inhibition of neointimal hyperplasia (restenosis) and platelet aggregation (thrombosis), while the peptide matrix promotes endothelial cell binding and vessel wall healing. Developed at the University of Alabama at Birmingham, Bionanomatrix-CS is currently in the IND-enabling phase of development for coronary stent applications.
- Brand names
- Bionanomatrix
- Other names
- Bionanomatrix CSBionanomatrix (NO-releasing coating)
02
Targets
sGC (Soluble Guanylyl Cyclase)
Beyond the preview
Go deeper on Bionanomatrix-CS.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Bionanomatrix-CS.