Drug intelligence / Profile preview

BIOSTEP

Development stage
Unknown
Lead developer
Smith & Nephew
Modality
Recombinant Proteins and Enzymes
Administration
Topical
01

Overview

BIOSTEP is a collagen matrix wound dressing developed by Smith+Nephew, designed for the management of chronic and acute wounds. It is composed of a porcine collagen matrix that functions by deactivating excess matrix metalloproteinases (MMPs), which are often elevated in chronic wounds and can impede the healing process. By modulating the wound environment and maintaining a moist balance for up to six days, BIOSTEP promotes the formation of granulation tissue. It is indicated for various wound types, including pressure injuries, diabetic foot ulcers, venous leg ulcers, and burns. A version containing silver, BIOSTEP Ag, is also available for wounds where bacterial control is required.

Brand names
BIOSTEPBIOSTEP Ag
02

Targets

MMP12 (Macrophage Metalloelastase)

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