Biosuccinium S

Biosuccinium S is a high-purity, 100% bio-based pharmaceutical grade of succinic acid produced via a proprietary yeast-based fermentation process. Originally developed by Reverdia (a joint venture between DSM and Roquette), it serves as a sustainable alternative to petroleum-derived succinic acid. In the pharmaceutical industry, Biosuccinium S is utilized as a versatile building block for the synthesis of active pharmaceutical ingredients (APIs), a buffering agent in drug formulations, and a counter-ion for the production of succinate salts. In dermo-cosmetics and topical therapeutics, it is increasingly employed as an active ingredient due to its antimicrobial properties—specifically against *Cutibacterium acnes*—and its role as an endogenous ligand for the succinate receptor 1 (SUCNR1/GPR91), which modulates cellular metabolism and inflammatory responses. Its high chemical purity and low carbon footprint make it suitable for sensitive applications in personal care, nutraceuticals, and pharmaceutical manufacturing.

Brand names

Biosuccinium SBiosuccinium

Other names

succinic acidbio-based succinic acidbutanedioic acidE363E-363E 363