Drug intelligence / Profile preview

Biotene Dry Mouth Oral Rinse

Development stage
Unknown
Lead developer
HALEON
Modality
Small Molecules
Administration
Topical
01

Overview

Biotene Dry Mouth Oral Rinse is a commercially available over-the-counter oral rinse formulated as a saliva substitute to relieve the symptoms of dry mouth (xerostomia). It is a non-biologic, small molecule topical formulation containing a combination of moisturizers and humectants, including glycerin, xylitol, sorbitol, and propylene glycol, and is free of alcohol, sugar, and sodium lauryl sulfate (SLS). The rinse acts by retaining water and lubricating the oral mucosal tissue, providing up to 4 hours of symptomatic relief per use. It is being evaluated in clinical trials, such as the 'BIG DRY' perioperative trial in New Zealand led by Dr. Doug Campbell, to assess its efficacy in reducing preoperative dry mouth in elective adult surgical patients compared to a water mouth rinse.

Brand names
Biotene Dry Mouth Oral RinseBiotene Dry Mouth Fresh Mint Oral RinseBiotene Oral Rinse
Other names
Biotene mouthwashBiotene saliva substitute

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