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**Biotene OralBalance** is a nonprescription oral moisturizing and saliva-substitute gel used to relieve symptoms of xerostomia. Its concentrated lubricating and humectant gel matrix forms a physical coating in the oral cavity, retains moisture, reduces friction-related discomfort, and supports swallowing; formulations have also contained a salivary-enzyme system intended to help maintain a healthy oral environment. It is marketed as an alcohol-free, sugar-free, flavor-free gel that can provide dry-mouth symptom relief for up to four hours. The product has also been studied as timed oral care in mechanically ventilated neonates to assess feasibility and potential reduction of ventilator-associated pneumonia risk. ([biotene.com](https://www.biotene.com/dry-mouth-products/moisturizing-gel/))
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