Drug intelligence / Profile preview

Bioven

Development stage
Phase 3
Lead developer
Biopharma
Modality
Recombinant Proteins and Enzymes
Administration
Intravenous
01

Overview

**Bioven** is a human normal immunoglobulin for intravenous administration (IVIG), containing at least 98% immunoglobulin G (IgG), formulated as a 5% or 10% infusion solution with glycine and water for injection. It is indicated for replacement immunotherapy in primary immunodeficiency syndromes (e.g., congenital agammaglobulinemia, hypogammaglobulinemia, severe combined immunodeficiency, Wiskott-Aldrich syndrome) and secondary immunodeficiencies (e.g., cytopenias from leukemia or chemotherapy, severe bacterial/viral infections, post-bone marrow transplant). Additional uses include autoimmune diseases such as idiopathic thrombocytopenic purpura, Guillain-Barré syndrome, Kawasaki syndrome, and as adjunctive therapy for severe COVID-19 pneumonia. Developed and manufactured in Ukraine by Biopharma Plasma, it provides broad polyclonal antibodies to support immune function in patients with antibody deficiencies or acute infections.

Brand names
BiovenBioven Mono
Other names
Human normal immunoglobulinIVIGBioven 10%
02

Targets

DC-SIGN (Dendritic cell-specific intercellular adhesion molecule-3-grabbing non-integrin)FCGRT (Neonatal crystallizable fragment receptor)NeuraminidaseFcγR (Low affinity immunoglobulin gamma Fc region receptor II-c)

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