biphasic insulin aspart

Biphasic insulin aspart is a premixed suspension consisting of rapid-acting soluble insulin aspart and intermediate-acting insulin aspart protamine crystals. This formulation is designed to mimic the physiological insulin response by providing both a rapid onset of action to control postprandial glucose spikes and a prolonged duration of action to maintain basal insulin levels. It is primarily indicated for the treatment of diabetes mellitus in adults, adolescents, and children. The most common ratio is 30% soluble insulin aspart and 70% insulin aspart protamine (NovoMix 30), though other ratios like 50/50 also exist. Several pharmaceutical companies, including Yichang Dongyangguang Yangtze River Pharmaceutical (HEC Pharm) and Tonghua Dongbao Pharmaceutical, have developed biosimilar versions of this insulin mixture.

Brand names

NovoMix 30NovoMix30NovoMix-30NovoMix 50NovoMix50NovoMix-50NovoMix 70NovoMix70NovoMix-70

Other names

Insulin Aspart 30Insulin Aspart 50Biphasic Insulin Aspart 30/70Biphasic Insulin Aspart 50/50