Drug intelligence / Profile preview

biphasic isophane insulin

Development stage
Unknown
Lead developer
Aristopharma
Modality
Recombinant Proteins and Enzymes, Peptides
Administration
Subcutaneous
01

Overview

Insulet 30/70 is a biphasic recombinant human insulin preparation developed by Aristopharma for the management of diabetes mellitus. It consists of a mixture of 30% soluble (regular) insulin and 70% isophane (NPH) insulin. The soluble component provides a rapid onset of action to control postprandial glucose levels, while the isophane component provides a prolonged duration of action for basal insulin coverage. By binding to the insulin receptor, it stimulates glucose uptake in skeletal muscle and fat, while inhibiting hepatic glucose production, thereby regulating glucose metabolism. It is produced using recombinant DNA technology and is administered via subcutaneous injection.

Brand names
Insulet 30/70
Other names
insulin human (rDNA) 30/70biphasic insulin humanrecombinant human insulin 30/70
02

Targets

IGF-1R (Insulin-like growth factor 1 receptor)INSR (Insulin receptor)

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