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Biqi Capsule (痹祺胶囊) is a traditional Chinese medicine (TCM) compound preparation used primarily for the treatment of rheumatoid arthritis and related musculoskeletal disorders. Its formula is based on classical TCM principles, combining ten herbal ingredients including processed Strychnos nux-vomica (马钱子粉), Pheretima aspergillum (地龙), Codonopsis pilosula (党参), Poria cocos (茯苓), Atractylodes macrocephala (白术), Ligusticum wallichii (川芎), Salvia miltiorrhiza (丹参), Panax notoginseng (三七), Achyranthes bidentata (牛膝), and Glycyrrhiza uralensis (甘草)[1][3][6][9]. The capsule is indicated for replenishing qi and blood, dispelling wind-dampness, promoting blood circulation, and relieving pain. It is clinically used for symptoms such as muscle and joint soreness, swelling or deformity of joints, muscle atrophy, fatigue due to qi-blood deficiency, as well as rheumatic diseases like rheumatoid arthritis, lumbar muscle strain, soft tissue injuries[1][4][5][6]. Mechanistically, its anti-inflammatory effects are attributed to active components such as cryptotanshinone from Salvia miltiorrhiza and brucine/strychnine from Strychnos nux-vomica; these compounds have been shown to inhibit nitric oxide production and reduce inflammatory cytokines in preclinical studies[6]. The product has been widely used in China since 1991 with clinical evidence supporting its efficacy in rheumatology[9].
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