Birla Inst. of Technology and Science HK2 compound 12

Birla Inst. of Technology and Science HK2 compound 12: sourced facts only. name: "Our findings identified a novel BTZ-based HK2 inhibitor compound 12 with HK2 IC50 of 56 nM and a ∼50-fold improvement in HK2 inhibitory potency over initial lead compound H2, that not only exhibits potent anti-cancer activity but also induces mitophagy, providing a new mechanism for OSCC therapy." [PMID:41455280]; target: "Our findings identified a novel BTZ-based HK2 inhibitor compound 12 with HK2 IC50 of 56 nM and a ∼50-fold improvement in HK2 inhibitory potency over initial lead compound H2, that not only exhibits potent anti-cancer activity but also induces mitophagy, providing a new mechanism for OSCC therapy." [PMID:41455280]; developer: "Department of Chemistry, Birla Institute of Technology and Science, Pilani Hyderabad Campus, Hyderabad, 500078, Telangana, India." [PMID:41455280]