Drug intelligence / Profile preview

bIRV AB

Development stage
Unknown
Lead developer
Pfizer
Modality
mRNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Vaccines & Immunotherapeutics
Administration
Intramuscular
01

Overview

**bIRV AB** is an investigational bivalent influenza modified RNA vaccine developed by BioNTech and Pfizer. It is designed to target one influenza A strain and one influenza B strain, using modRNA to direct in vivo production of vaccine antigens and elicit protective humoral and cellular immune responses. It was evaluated as part of Pfizer's C4781001 Phase 1/2 influenza modRNA vaccine study; the bIRV A/B formulation was assessed in the Phase 1 substudy in healthy adults aged 65 to 85 years. ([pfizer.com](https://www.pfizer.com/sites/default/files/plsr-studies/C4781001_SSA_B_combined_PLS_0.pdf))

Other names
bIRV AB
02

Targets

HA (Hemagglutinin)

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