bismuth

Bismuth is a heavy metal compound used in the treatment of *Helicobacter pylori* infection, often as part of a quadruple therapy regimen. In the context of research at National Taiwan University Hospital, it is being studied for its direct antimicrobial effects and how intragastric pH influences its efficacy. Bismuth acts by lysing *H. pylori* cells, inhibiting bacterial enzymes such as urease and alcohol dehydrogenase, and preventing adherence to the gastric mucosa. It does not typically develop bacterial resistance, making it a crucial component in overcoming antibiotic-resistant strains.

Other names

bismuth saltsbismuth compounds