Drug intelligence / Profile preview

bismuth hydroxide

Development stage
Unknown
Lead developer
Zhejiang Xinmingzhu Pharmaceutical
Modality
Small Molecules
Administration
Oral
01

Overview

Bismuth hydroxide is an inorganic compound primarily utilized as an active pharmaceutical ingredient (API) in the production of gastrointestinal medications. As a member of the bismuth salt family, it is employed for its antacid and gastroprotective properties. The therapeutic effect of bismuth compounds typically involves the formation of a protective coating over gastric ulcers and mucosal erosions, which shields the tissue from gastric acid and pepsin. Additionally, bismuth salts exhibit direct bactericidal activity against *Helicobacter pylori* by inhibiting bacterial enzymes and cell wall synthesis. Zhejiang Xinmingzhu Pharmaceutical manufactures bismuth hydroxide as a raw material for export and for use in oral solid dosage forms, categorizing it as a commodity generic or over-the-counter (OTC) chemical rather than a novel biotech candidate.

Other names
氢氧化铋bismuth(III) hydroxide
02

Targets

UreaseUreG (Urease accessory protein UreG (Helicobacter pylori))

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