Drug intelligence / Profile preview

bismuth sodium tartrate

Development stage
Phase 4
Modality
Small Molecules
Administration
Oral
01

Overview

Bismuth sodium tartrate is an inorganic compound containing bismuth, sodium, and tartrate ions. It is classified as a bismuth salt and functions as a coordination complex of bismuth, recognized by its chemical formula C4H2BiNaO6. Historically, bismuth tartrate compounds have had antimicrobial activity and have been studied and used in the treatment of gastrointestinal conditions and certain bacterial infections. The compound’s mechanism of action involves the antimicrobial property of bismuth ions, which disrupt microbial enzymes, and provide cytoprotective effects in the gastrointestinal tract. However, specific modern pharmaceutical indications and formulations of bismuth sodium tartrate are not widely documented; related bismuth tartrate salts (such as potassium bismuth tartrate) were used medicinally in the early 20th century[1][5]. Bismuth ions generally act as enzyme inhibitors, contributing to bactericidal effects, especially against Helicobacter pylori and related pathogens, and offer local protective properties on the gastric mucosa.

Brand names
TartrolNatrol
Other names
bismuth sodium tartratetartaric acidbismuth sodium saltsodium bismuthyl tartrate
02

Targets

Microbial metalloproteins and thiol-containing enzymes

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