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bisoprolol EG
- Development stage
- Unknown
- Lead developer
- EG
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Bisoprolol EG is a generic pharmaceutical formulation of bisoprolol fumarate, a highly cardioselective beta-1 adrenergic receptor antagonist. It is primarily indicated for the management of hypertension, angina pectoris, and stable chronic heart failure with reduced systolic left ventricular function. By selectively inhibiting beta-1 receptors in the heart, bisoprolol reduces heart rate, cardiac output, and blood pressure, while also decreasing myocardial oxygen demand. The drug is marketed by EG (Eurogenerics) and has been the subject of clinical research at institutions such as Ziekenhuis Oost Limburg, particularly concerning its role in patients with heart failure in remission (recovered ejection fraction) to evaluate the safety and efficacy of treatment maintenance versus withdrawal.
- Brand names
- Bisoprolol EG
- Other names
- bisoprolol fumarate EG
02
Targets
ADRB2 (β2)KCNQ (Potassium voltage-gated channel subfamily Q (Kv7))ADRB1 (β1)KCNH2 (Voltage-gated potassium channel subfamily H member 2)
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