Drug intelligence / Profile preview

BIV201

Development stage
Unknown
Lead developer
BioVie
Modality
Peptides
Administration
Continuous Infusion
01

Overview

BIV201 is a continuous infusion formulation of terlipressin acetate being developed for the treatment of ascites due to liver cirrhosis. It is administered via a portable infusion pump, which delivers terlipressin slowly throughout the day rather than as a single bolus injection. This approach has shown to reduce the incidence of drug-related severe adverse events. BioVie has developed a novel liquid formulation of terlipressin that has demonstrated stability at room temperature for at least 12 months, which is considered an important advantage for treating ascites patients in home care settings.

Other names
continuous infusion terlipressin
02

Targets

AVPR2 (Arginine vasopressin V2 receptor)AVPR1B (Vasopressin V1b Receptor)AVPR1A (Arginine vasopressin receptor 1A)

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