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The regimen 'bivalent oral poliovirus vaccine (bOPV) + DTP-HB-Hib vaccine + inactivated poliovirus vaccine (IPV)' is a combination immunization schedule developed by PT Bio Farma. It was specifically evaluated in Indonesian infants to facilitate the global transition from trivalent oral poliovirus vaccine (tOPV) to a schedule using bOPV and IPV. The regimen includes Bio Farma's bOPV (containing live attenuated poliovirus types 1 and 3), the pentavalent vaccine Pentabio® (containing diphtheria toxoid, tetanus toxoid, whole-cell pertussis, hepatitis B surface antigen, and Haemophilus influenzae type b conjugate), and a standalone IPV (providing inactivated poliovirus types 1, 2, and 3). This comprehensive schedule provides protection against poliomyelitis, diphtheria, tetanus, pertussis, hepatitis B, and Hib-related diseases.
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