Drug intelligence / Profile preview

BK-FLU

Development stage
Unknown
Lead developer
Research Foundation for Microbial Diseases of Osaka University
Modality
Vaccines & Immunotherapeutics
Administration
Subcutaneous
01

Overview

BK-FLU is an investigational cell-culture-derived inactivated influenza vaccine developed by The Research Foundation for Microbial Diseases of Osaka University (BIKEN). Unlike traditional influenza vaccines that are produced in embryonated chicken eggs, BK-FLU is manufactured using cell-culture technology, which offers advantages such as a more scalable production process and the avoidance of egg-adaptive mutations that can compromise vaccine efficacy. The vaccine is designed to provide protection against seasonal influenza by inducing the production of neutralizing antibodies against viral hemagglutinin. It is currently undergoing Phase II clinical evaluation in Japan, where it is administered as a subcutaneous injection to healthy adults.

Other names
BIKEN influenza vaccineCell-culture-derived influenza vaccine
02

Targets

HA0 (Influenza B virus hemagglutinin)

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