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BL-004
- Development stage
- Preclinical
- Lead developer
- Bloom Science
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BL-004 is a preclinical-stage microbial therapy being developed by Bloom Science for the treatment of amino acid disorders. The drug's mechanism of action involves the biochemical conversion of toxic amino acids into non-toxic metabolites, likely mediated by engineered or specific strains of bacteria within the gut microbiome. By degrading harmful amino acids before they can accumulate systemically, BL-004 aims to provide a therapeutic option for metabolic conditions where amino acid management is critical, leveraging Bloom Science's expertise in the gut-brain axis and live biotherapeutic products.
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