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BL-008
- Development stage
- Preclinical
- Lead developer
- Bloom Science
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BL-008 is a preclinical-stage therapeutic candidate being developed by Bloom Science for the treatment of Alzheimer's disease. It is designed to modulate neuroinflammation, a key driver of neurodegeneration, through the gut-brain axis. Bloom Science utilizes a platform focused on identifying specific microbes and metabolites that influence neurological health. BL-008 is categorized as a live biotherapeutic product (LBP), intended to regulate systemic immune and metabolic pathways to potentially slow the progression of Alzheimer's pathology.
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