Drug intelligence / Profile preview

black raspberry extract gel

Development stage
Unknown
Lead developer
Tianjin Medical University Cancer Institute and Hospital
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Vaginal
01

Overview

A vaginal gel formulation containing black raspberry extract developed by Tianjin Medical University Cancer Institute and Hospital. It is specifically designed to treat Human Papillomavirus (HPV) infection in patients with cervical intraepithelial neoplasia (CIN) following cervical conization. The extract, derived from Rubus occidentalis, contains bioactive compounds such as anthocyanins and ellagitannins that exhibit anti-viral, anti-inflammatory, and anti-proliferative properties. In a Phase 2 multicenter trial, the gel demonstrated a significant increase in HPV clearance (72.8% vs 15.8% for placebo) and a substantial reduction in viral load, suggesting its potential as a non-invasive therapeutic option for post-surgical HPV management.

Other names
Composite Gel Containing Black Raspberryblack raspberry extract vaginal gel

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