blackcurrant emulsion

Blackcurrant emulsion is an investigational oral formulation of blackcurrant seed oil (BSO) derived from *Ribes nigrum*. It is primarily studied for the prevention and management of atopic dermatitis (DOID_3310), particularly in infants and high-risk pediatric populations. The oil is a rich source of essential fatty acids, including gamma-linolenic acid (GLA), stearidonic acid (SDA), and alpha-linolenic acid (ALA). In patients with atopic dermatitis, the activity of the delta-6 desaturase enzyme, which converts linoleic acid to GLA, is often impaired. By providing preformed GLA and SDA, the emulsion bypasses this metabolic bottleneck, increasing levels of dihomo-gamma-linolenic acid (DGLA). DGLA serves as a precursor to the anti-inflammatory prostaglandin E1 (PGE1) and is converted into 15-hydroxyeicosatrienoic acid (15-HETrE), which inhibits the production of pro-inflammatory leukotrienes. The emulsion formulation is typically used in clinical trials to enhance the oral bioavailability and palatability of the seed oil for young children.

Other names

blackcurrant seed oil emulsionBCSO emulsionRibes nigrum seed oil emulsionblackcurrant oil emulsion