Drug intelligence / Profile preview

blackraspberry powder

Development stage
Phase 1
Lead developer
BerriHealth
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Blackraspberry powder is a dietary supplement made from the freeze-dried fruit of the black raspberry (Rubus occidentalis). It is rich in bioactive compounds such as anthocyanins, ellagic acid, ellagitannins, and quercetin. These compounds are believed to have antioxidant, anti-inflammatory, and potential chemopreventive properties. Laboratory and early clinical studies suggest that concentrated blackraspberry powder may help protect against certain cancers (including colon, esophageal, skin cancers), modulate immune function by affecting dendritic cells, improve vascular health by reducing vessel stiffness and cholesterol levels in metabolic syndrome patients, and reduce inflammation markers like IL-6. The mechanism of action appears to involve antioxidant activity (scavenging free radicals), inhibition of angiogenesis (blocking blood supply to tumors), DNA hypomethylation effects (modifying gene expression related to cancer progression), and modulation of inflammatory cytokines[1][3][4][6][8]. Blackraspberry powder is typically consumed orally as a supplement or added to foods; it has also been studied in topical gel formulations for oral lesions[7]. While promising for several indications including cancer prevention and cardiovascular health support, robust clinical evidence remains limited.

Brand names
BerriHealth Black Raspberry Powder
Other names
black raspberry powderfreeze-dried black raspberry powderRubus occidentalis powder
02

Targets

HDAC2 (Histone deacetylase 2)HDAC1 (Histone Deacetylase 1)DNMT3B (DNA (cytosine-5)-methyltransferase 3B)TUBB (Tubulin (alpha and beta subunits))MBD2 (Methyl-CpG-binding domain protein 2)NF-κB

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