Drug intelligence / Profile preview

bli-1301

Development stage
Unknown
Lead developer
BioLite
Modality
Small Molecules
Administration
Oral
01

Overview

BLI-1301 is a natural anti-cancer ingredient extracted from a special fungus using a patented process developed by Yukiguni Maitake Co. Ltd., Japan. It is classified as an immunomodulator and small molecule drug. The primary indication for BLI-1301 is the treatment of myelodysplastic syndromes (MDS), a group of rare hematological cancers characterized by ineffective hematopoiesis and increased risk of infection due to cytopenias. Animal and human studies have shown that oral administration of BLI-1301 can enhance the immune system, repair hematopoietic stem cells, and potentially reduce infection risk in MDS patients. The drug has also been investigated for breast cancer[6][2][1].

Other names
Maitake D-fractionGrifola frondosa extractbeta-glucan from Grifola frondosa
02

Targets

αMβ2 (Integrin αMβ2)TLR2 (Toll-like Receptor 2)LacCer (Lactosylceramide)TLR4 (Toll-like receptor 4)CLEC7A (Dectin-1)CD36 (CD36 antigen)

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