Drug intelligence / Profile preview

BLI801

Development stage
Phase 3
Lead developer
Braintree Laboratories
Modality
Small Molecules
Administration
Oral
01

Overview

**BLI801** is an investigational oral osmotic laxative developed by Braintree Laboratories for constipation. It is a reformulated sulfate-salt solution containing sodium sulfate and potassium sulfate. Poorly absorbed sulfate ions retain water in the intestinal lumen, softening stool and increasing bowel motility and evacuation. BLI801 was evaluated in completed Phase 2 and Phase 2/3 clinical studies in adults with chronic idiopathic constipation and non-idiopathic constipation, including medication-associated constipation; no marketed brand or regulatory approval for BLI801 was identified. ([cdn.clinicaltrials.gov](https://cdn.clinicaltrials.gov/large-docs/08/NCT02822508/Prot_SAP_000.pdf))

Other names
BLI801 LaxativeBLI-801 LaxativeBLI 801 Laxative

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