Blood component B-Università degli Studi di Ferrara-beta-thalassemia

Blood component B-Università degli Studi di Ferrara-beta-thalassemia refers to a specific preparation of Packed Red Blood Cells (PRBCs) utilized in a Phase 4 clinical trial (NCT02492607) conducted by the Università degli Studi di Ferrara. This blood component is produced using a 'whole blood filtration' method, where leukoreduction is performed on the whole blood unit prior to the separation of plasma and red blood cells. This is contrasted with 'red cell filtration' (Blood component A), where separation occurs before leukoreduction. The primary indication is the management of transfusion-dependent beta-thalassemia, where the goal is to maintain adequate hemoglobin levels and minimize transfusion-related complications such as iron overload. The study evaluates whether the specific processing method impacts transfusion indices and the overall clinical regimen for these patients.

Other names

PRBCs obtained by leukoreduction of whole blood and successive separation of plasma and RBCsWhole blood filtration PRBCs