blood heat clearing decoction

Blood heat clearing decoction is a traditional Chinese medicine (TCM) herbal formula used primarily for conditions associated with the "blood-heat" syndrome in TCM theory. It is also known as liang xue huo xue decoction (LXHXD). The formula typically contains a combination of herbs aimed at "clearing heat," "cooling the blood," and promoting circulation to remove stasis. Its mechanism of action involves anti-inflammatory effects, including downregulation of inflammatory mediators such as COX2, prostaglandin E2 (PGE2), tumor necrosis factor-alpha (TNF-α), interleukin-6 (IL-6), and interleukin-1β (IL-1β). It has been shown to modulate the miR-26b-5p/COX2 axis to inhibit inflammation[1][3]. Clinically, it has been studied for use in acute soft tissue injury and psoriasis vulgaris with blood heat syndrome[1][3]. The formulation may vary but often includes herbs like Radix Salviae Miltiorrhizae, Rhizoma Gastrodiae, Typhonium flagelliforme, Mongolian snakegourd shell, Fructus Momordicae charantiae, and Radix Polygoni Multiflori[5].

Other names

liang xue huo xue decoctionLXHXDblood-heat clearing and activating decoction