Drug intelligence / Profile preview

Blue M Gel

Development stage
Phase 1
Lead developer
Bluem
Modality
Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

Blue M Gel (often stylized as blue®m) is a topical oral care formulation developed by BlueM, a company founded by Dutch oral surgeon Dr. Peter Blijdorp. The gel is specifically designed to enhance wound healing and manage inflammatory conditions in the oral cavity through the controlled release of active oxygen. Its mechanism of action involves increasing oxygen tension at the wound site, which promotes angiogenesis, stimulates collagen synthesis, and creates an environment that inhibits the growth of anaerobic bacteria. The formulation typically includes sodium perborate as the primary oxygen source, along with organic honey (which releases hydrogen peroxide enzymatically), lactoferrin (an iron-binding protein with antimicrobial properties), and xylitol. Blue M Gel is used clinically for the treatment of periodontitis, peri-implantitis, and to accelerate healing after oral surgeries, such as secondary cleft lip correction.

Brand names
Blue M Gelblue®m oral gel
Other names
active oxygen releasing gel
02

Targets

LPS (Bacterial cell wall components (Lipopolysaccharide and negatively charged structures))Fe2+ (Ferrous iron)

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