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BMC202

Development stage
Preclinical
Lead developer
Biomica
Modality
Small Molecules
01

Overview

BMC202 is a small-molecule drug candidate being developed by Biomica for the treatment of *Clostridioides difficile* Infection (CDI). While Biomica's core pipeline primarily features Live Bacterial Products (LBPs), BMC202 utilizes a small-molecule approach to target and neutralize the toxins produced by *C. difficile* bacteria. These toxins are the primary virulence factors responsible for the inflammation, mucosal damage, and severe diarrhea associated with the infection. By neutralizing these toxins directly, BMC202 aims to reduce the clinical severity of CDI and potentially prevent the recurrence of the disease without the broad-spectrum antimicrobial activity that can further disrupt the gut microbiome.

Other names
nanI null mutant of type D strain CN3718
02

Targets

TcdB (Clostridioides difficile large clostridial toxin family)

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