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BMC321
- Development stage
- Preclinical
- Lead developer
- Biomica
- Modality
- Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BMC321 is a rationally designed live biotherapeutic product being developed by Biomica for inflammatory bowel disease, including ulcerative colitis and Crohn's disease. The product consists of a defined consortium of selected live bacterial strains intended to restore microbial diversity and functional activity in the gut microbiome and to reduce gut mucosal inflammation. Rather than acting as a conventional small molecule or biologic against a single molecular target, BMC321 is a microbiome-based therapeutic designed to deliver multiple beneficial functions through its constituent microbes, with the overall therapeutic goal of modulating intestinal inflammation in IBD.
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