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BMC427
- Development stage
- Preclinical
- Lead developer
- Biomica
- Modality
- Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
- Administration
- Oral
01
Overview
BMC427 is a microbiome-based therapeutic candidate developed by Biomica, a subsidiary of Evogene, for the treatment of Irritable Bowel Syndrome (IBS). Identified using Evogene's MicroBoost AI engine, BMC427 is a live biotherapeutic product (LBP) consisting of a rationally designed consortium of bacterial strains. The program aims to restore microbial balance in the gut to alleviate symptoms associated with IBS. Biomica received strategic investment from Shanghai Healthcare Capital to advance this and other pipeline candidates into clinical development.
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