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BMD-002
- Development stage
- Preclinical
- Lead developer
- BIORCHESTRA
- Modality
- Antisense Oligonucleotides (ASOs) → Long RNA Therapeutics → RNA Therapeutics → Nucleic Acid Therapeutics, Single-strand DNA → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics, Modified DNA Oligonucleotides → Antisense DNA → DNA Therapeutics → Nucleic Acid Therapeutics
01
Overview
BMD-002 is an antisense oligonucleotide (ASO) therapeutic being developed by BIORCHESTRA for the treatment of epilepsy. The drug utilizes BIORCHESTRA's proprietary Brain Targeting Drug Delivery System (BDDS™), a polymeric nanoparticle technology designed to transport RNA-based therapeutics across the blood-brain barrier (BBB) following systemic administration. While the specific molecular target of BMD-002 remains undisclosed, the program is designed to modulate genetic expression associated with epileptic pathways. As of early 2024, the candidate is in the discovery and preclinical stages of development.
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