Drug intelligence / Profile preview

BMEC-1217B

Development stage
Phase 1
Lead developer
Medigreen Biotechnology
Modality
Small Molecules
01

Overview

BMEC-1217B is an orally administered investigational anti-asthma agent developed by Medigreen Biotechnology. It is a modified formulation based on traditional Chinese medicine, specifically a version of Liu-Wei-Di-Huang-Wan, with the ratio of components optimized for pharmacological activity. Preclinical studies indicate that BMEC-1217B inhibits the synthesis of key pro-inflammatory mediators such as cysteinyl leukotrienes, interleukin-4 (IL-4), and tumor necrosis factor-alpha (TNF-alpha), which are involved in the pathophysiology of allergic asthma. In animal models, it has demonstrated improvement in lung function and reduction in airway hyperreactivity. The drug has undergone Phase 1 clinical trials to assess safety and tolerability in healthy volunteers[1][2][5].

02

Targets

TNFA (Tumor necrosis factor alpha (soluble))ALOX5 (Arachidonate 5-lipoxygenase)IL-4 (Interleukin 4)

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