Drug intelligence / Profile preview

BMS-919373 + atorvastatin

Development stage: Unknown
Lead developer: Bristol Myers Squibb
Modality: Small Molecules
Administration: Oral

Overview

This drug refers to a combination of **BMS-919373**, a highly functionalized quinazoline investigated as a selective and potent blocker of the voltage-gated potassium channel subunit Kv1.5 (IKur current), and **atorvastatin**, a widely used statin for the reduction of cholesterol and prevention of cardiovascular disease. BMS-919373 was developed for use in cardiovascular conditions such as atrial fibrillation, operating via selective blockade of Kv1.5 to modulate atrial electrophysiology[1]. Atorvastatin is a synthetic small molecule HMG-CoA reductase inhibitor (statin), which lowers cholesterol by inhibiting its biosynthesis and upregulates LDL receptor activity in the liver. The combination was studied pharmacokinetically in clinical trials to assess drug-drug interactions and potential combined effects on healthy subjects[3].

Other names: BMS 919373BMS919373BMS-919373

Targets

KCNA5 (Ultra-rapid delayed rectifier potassium channel)

Beyond the preview

Go deeper on BMS-919373 + atorvastatin.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on BMS-919373 + atorvastatin.

Explore the full profile