Drug intelligence / Profile preview

BMS-986279

Development stage: Unknown
Lead developer: Bristol Myers Squibb
Modality: Alpha Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics, Beta Emitters → Antibody-Radionuclide Conjugates → Antibody Conjugates → Antibody-Based Therapeutics
Administration: Intravenous

Overview

BMS-986279 is a zirconium-89-labeled monoclonal antibody-based PET imaging agent developed for targeting fucosyl-GM1 (fuc-GM1), a membrane glycolipid antigen expressed in small cell lung cancer (SCLC). BMS-986279 is a modified version of BMS-986012, designed for use as a radiotracer in imaging studies. Its main use is to non-invasively assess and visualize the expression of fuc-GM1 in tumor tissue using PET-CT, supporting the selection or evaluation of immunotherapy strategies that target this antigen. The radiotracer’s primary mechanism is high-affinity and selective binding to fuc-GM1, providing tumor localization through imaging rather than direct therapeutic intervention.[1][4][5]

Other names: 89Zr-DFO-BMS-98601289Zr-labeled BMS-986012

Targets

Fuc-GM1 (Fucosyl-GM1 ganglioside)

Beyond the preview

Go deeper on BMS-986279.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Follow clinical development from study design and recruitment through results.

Trial phase
Status
Readouts

Indications & development

Explore development by indication, patient population, and geography.

Indications
Development status
Countries

Licensing & deals

Trace asset ownership, licensing agreements, and commercial partnerships.

Partners
Deal terms
Milestones

Patents & exclusivity

Explore the patent landscape and regulatory exclusivity around an asset.

Patents
Expiration dates
Exclusivity

Competitive landscape

Compare development programs by target, modality, and indication.

Competing assets
Targets
Development stage

Research & analysis

Connect source evidence and development news to your research questions.

Publications
News
Analysis

Bring the full picture into focus.

See how Gosset can support your research on BMS-986279.

Explore the full profile