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BMS-986498 is a biologic drug candidate developed for autoimmune diseases. It is classified as a phase 1-ready biologic targeting the IL10 pathway, suggesting a mechanism involving modulation or agonism of interleukin-10 (IL-10), a cytokine with anti-inflammatory properties. The drug was initially developed by Bristol Myers Squibb and is being transferred to a new, yet unnamed, independent biotechnology company launched in partnership with Bain Capital. The focus for BMS-986498 is likely in diseases where alteration of immune tolerance or inflammation is beneficial, typical of autoimmune indications[7][9].
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