Drug intelligence / Profile preview

BN-101A

Development stage
Preclinical
Lead developer
Bio Eleven
Modality
Monoclonal Antibodies → Antibody-Based Therapeutics
01

Overview

BN-101A is a monoclonal antibody that functions as a PD-L1 inhibitor, blocking programmed cell death ligand 1 (PD-L1) to promote anti-cancer T-cell activity. Developed initially by Scripps Korea Antibody Institute and now advanced by BioEleven Co., Ltd., it has demonstrated efficacy in preclinical models of cancer. Samsung Biologics has partnered with BioEleven for its development and manufacturing as a third-generation cancer immunotherapy.

Other names
anti-PD-L1 antibody (Scripps Korea Antibody Institute)PD-L1 checkpoint inhibitor (Bioeleven)
02

Targets

CD274 (Programmed cell death protein 1 ligand 1)

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