Drug intelligence / Profile preview

boesenbergia pandurata extract

Development stage
Preclinical
Lead developer
Yonsei University
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Boesenbergia pandurata extract, derived from the tropical plant fingerroot, is a natural product rich in the cyclohexenyl chalcone panduratin A. It exhibits a broad range of biological activities, including anti-inflammatory, antioxidant, antibacterial, and anti-obesity properties. Research has focused on its potential to treat sarcopenia by activating the PI3K/Akt/mTOR pathway and inhibiting proteolysis via FoxO3a. Additionally, it has been investigated for oral health (periodontitis), skin hydration and anti-aging, and certain cancers. While primarily studied as a functional food or nutricosmetic ingredient, its development is largely academic, with significant research conducted at Yonsei University.

Other names
fingerroot extractBoesenbergia pandurata extract
02

Targets

PPARA (Peroxisome proliferator-activated receptor alpha)NF-κBTNFA (Tumor necrosis factor alpha (soluble))FOXO3 (Forkhead box protein O3)

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