Drug intelligence / Profile preview

boldo leaf extract

Development stage
Unknown
Modality
Small Molecules
Administration
Oral, Topical
01

Overview

Boldo leaf extract is an herbal preparation derived from the leaves of the *Peumus boldus* Molina tree, native to central Chile. The extract contains a variety of bioactive compounds, most notably the aporphine alkaloid boldine, along with flavonoids and essential oils. It is primarily recognized for its antioxidant, choleretic, and hepatoprotective properties. In human medicine, it is traditionally used to treat dyspepsia, mild gastrointestinal spasms, and hepatobiliary dysfunction. In veterinary applications, particularly in poultry production, it is used as a dietary supplement to mitigate the adverse effects of heat stress by enhancing the antioxidant defense system, reducing lipid peroxidation, and improving overall growth performance.

Other names
Peumus boldus extractBoldo extract
02

Targets

GPX4 (Glutathione peroxidase 4)Misfolded SOD1

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