Drug intelligence / Profile preview

Bomacorin

Development stage
Unknown
Lead developer
Hevert-Arzneimittel
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Bomacorin is a traditional herbal medicine containing a high-dose dry extract of hawthorn leaves with flowers (*Crataegus* species). It is developed and marketed by Hevert-Arzneimittel (originating from Johannes Bürger Ysatfabrik) for the treatment of mild forms of heart failure, specifically declining cardiac performance corresponding to NYHA (New York Heart Association) stage II (or stage B). The active ingredients in hawthorn extract, such as flavonoids and oligomeric procyanidins, help strengthen the heart muscle, improve blood flow and oxygen supply to the coronary arteries, and regulate cardiac rhythm.

Brand names
BomacorinBomacorin 450 mg WeißdorntablettenBomacorin 450mg Hawthorn NBomacorin450mg Hawthorn NBomacorin-450mg Hawthorn N
Other names
Crataegus leaves with flowers dry extractWeißdornblätter mit Blüten Trockenextrakthawthorn leaves with flowers dry extract
02

Targets

ATP1A (Sodium/potassium-transporting ATPase)PDE (Phosphodiesterase family)NOS3 (eNOS)

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