Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
bone marrow aspirate concentrate (Mayo Clinic)
- Development stage
- Unknown
- Lead developer
- Mayo Clinic
- Modality
- Stem Cell Therapies → Cell Therapies
- Administration
- Intraarticular
01
Overview
Bone marrow aspirate concentrate (BMAC) is an autologous biologic therapy being investigated by Shane A. Shapiro, primarily at the Mayo Clinic, for the treatment of shoulder osteoarthritis. The therapy is prepared by harvesting bone marrow from the patient's own iliac crest and concentrating it through centrifugation. This process enriches the concentration of mononuclear cells, including mesenchymal stem cells (MSCs), and a variety of bioactive growth factors such as platelet-derived growth factor (PDGF), transforming growth factor-beta (TGF-β), vascular endothelial growth factor (VEGF), and bone morphogenetic proteins (BMPs). In the specific clinical protocol (NCT04826224), BMAC is administered into the shoulder joint following a Comprehensive Arthroscopic Management (CAM) surgical procedure. The goal of the therapy is to modulate the inflammatory environment of the osteoarthritic joint and promote tissue repair through the paracrine effects of the concentrated cells and growth factors.
- Other names
- BMACConcentrated bone marrow aspirateAutologous bone marrow aspirate concentrateConcentrated bone marrow aspirate-Shane A. Shapiro-shoulder osteoarthritis
Beyond the preview
Go deeper on bone marrow aspirate concentrate (Mayo Clinic).
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on bone marrow aspirate concentrate (Mayo Clinic).