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Bone marrow-derived mesenchymal stem cell concentrate is an autologous cell-based biologic therapy investigated for the treatment of chronic discogenic low back pain and lumbar spinal degeneration. The therapy involves harvesting mesenchymal stem cells (MSCs) from the patient's own bone marrow, typically via aspiration from the posterior iliac crest, followed by concentration and intradiscal injection. As a regenerative medicine approach, it leverages the multipotent, immunomodulatory, and anti-inflammatory properties of BM-MSCs to potentially stimulate disc repair and reduce local inflammation. This specific therapeutic approach is being evaluated by Green International University in Lahore, particularly in combination with specialized post-injection physical therapy protocols including myofascial release and isotonic exercises.
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